血清C反应蛋白水平在妊娠中期与早产关系的临床研究

The Blood Serum C-Response Protein Level the Clinical Research which Relates in the Pregnancy Intermediate Stage and the Premature Delivery

目的 探讨中期妊娠孕妇血清C反应蛋白（C-reactiveprotein，CRP）水平与早产的相关性。方法 采用散射比浊法测定131例妊娠在2006年3月至2008年6月14—24周孕妇血清CRP数值，并追踪其妊娠结局。结果 先兆早产组CRP明显高于对照组（P〈0．001）；保胎失败组CRP明显高于保胎成功组，血清CRP浓度为9．00mg／L可作为早产的诊断域值。结论 CRP水平增高，可作为预测早产的早期监测指标。

Objective To investigate the association of C-reactive protein （CRP） with preterm delivey. Method cases of pregnancy in 14—24 weeks from March 2006 to June 2008, to detect serum CRP by nephelometry, and track their pregnancy outcome. Results Serum C-reactive protein level in women with threatened pretermdelivery group was significantly higher than that of the control group （P〈0.001）, spontaneous delivery group was significantly higher than that of the indicated delivery group, and matemal serum CRP level 9.00mg/L was defined as the threshold vanle of pretermdelivery. Conclusions Clinical measurement of serum CRP value may serve as a specific marker in predicting premature delivery.