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子宫内膜异位症患者腹腔液中瘦素与VEGF水平的变化及意义 被引量:4

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摘要 目的:探讨子宫内膜异位症(内异症)患者腹腔液瘦素与VEGF水平的变化及其在内异症发病中的作用。方法:采用ELISA方法测定45例内异症患者和50例非内异症患者(对照组)腹腔液中瘦素及VEGF的含量,进行相关性分析。结果:两组间体重指数比较差异无显著性(P>0.05)。内异症患者腹腔液瘦素及VEGF水平与对照组比较差异有显著性(P<0.001)。Ⅰ~Ⅱ期与Ⅲ~Ⅳ期内异症患者腹腔液瘦素水平比较差异无显著性(P>0.05),腹腔液中VEGF水平在不同分期中比较差异有显著性(P<0.001),Ⅲ~Ⅳ期明显高于Ⅰ~Ⅱ期。腹腔液中瘦素及VEGF水平呈明显的正相关,相关系数r=0.714(P<0.001)。结论:内异症患者腹腔液中瘦素及VEGF水平明显升高,且腹腔液中VEGF水平与内异症疾病的严重程度有关。二者可能在内异症的发生、发展中相互关联且发挥重要作用。
出处 《中国妇幼保健》 CAS 北大核心 2009年第3期307-308,共2页 Maternal and Child Health Care of China
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同被引文献47

  • 1刘晖,徐渭贤,曹丽静,王辉,康泰.瘦素、瘦素受体和VEGF在结直肠癌中的表达及其生物学意义[J].河北医科大学学报,2009,30(7):673-676. 被引量:3
  • 2曹文东,杨涛,郝斌,皮兴涛,梁宏莉,续慧民,段红永,郭炳麟.瘦素及瘦素受体在乳腺癌中的表达及临床意义[J].中华实验外科杂志,2006,23(2):241-243. 被引量:22
  • 3尚慧玲,李光仪.散结镇痛胶囊治疗子宫内膜异位症疗效观察[J].中国中西医结合杂志,2007,27(1):24-24. 被引量:16
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