液基细胞学在子宫颈病变筛查中的价值

The value of Thinprep liquid based cytology for the screening of cervical lesions

目的:评价液基细胞学检查在宫颈病变筛查中的应用价值。方法:对经妇科检查初步诊断为宫颈炎的1800例患者行液基细胞学检查,其中阳性病例158例(ASCUS及以上病例),进一步行阴道镜下活检病理组织学检查,以病理学检查为金标准,细胞学结果与之相对照。结果:液基细胞学诊断为SCC、HSIL、LSIL的病例,病理符合率分别为100.00%、93.33%、60.00%。液基细胞学AGCUS34例中,有3例病理诊断为子宫内膜腺癌。结论:液基细胞学检查有助于宫颈癌、宫颈上皮内瘤变的检出;对细胞学为AGC的患者,有必要内膜分段诊刮,及时发现子宫内膜癌前病变及内膜癌。

Objective： To evaluate the value of Thinprep liquid based cytology in screening cervical lesions. Methods： 1 800 cases were detected by ThinPrep cytology according to TBS diagnosis system, the positive 158 cases were proceed the examination of cervical biopsyunder by colposcope. The ThinPrep cytology results were analysed, compared with the pathological diagnosis as the golden standard. Results： Among 158 cases diagnosed as SCC, HSIL, LSIL, the coincidences of ThinPrep cytology and pathological diagnosis were 100. 00%, 93.33% , 60. 00% and 52. 94%. Among 34 cases diagnosed as AGCUS by ThinPrep cytology, 3 cases were diagnosed as adeno- carcinoma of endometrium. Conclusion： ThinPrep cytology contribute to the detection of cervical cancer, intraepithelial neoplasia; cases di- agnosed as AGC should undergo fractional curettage of endometrium to detect precancerous lesion and endometrial cancer.