3Karkkainen M J, Haiko P, Sainio K, et al. Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins[J]. Nat lmmunol,2002,5( 1 ) : 74-80.
4Hamada K, Oike Y,Takakura N, et al. VEGF-C signaling pathways through VEGFR.-2 and VEGFR-3 in vasculoangiogenesis and hematopoiesis [J]. Blood,2000,96(12) : 3793-3800.
5Karpanen T, Egeblad M, Karkkainen M J, et al. Vascular endothelial growth factor-C promotes tumor lymphangiogenesis and intralymphatic tumor growth[ J ]. Cancer Res,2001,61 (5) : 1786-1790.
6Amioka T,Kitadai Y,Tanaka S,et al. Vascular endothelial growth factor-C expression predicts lymph node metastasis of human gastric carcinomas invading the submucosa [J]. Eur J Cancer,2002, 38(10) : 1413-1419.
7Krishnan J, Kirkin V,Steffen A,et al. Differential in vivo and in bitro expression of vascular endothelial growth factor (VEGF) -C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats [ J ]. Cancer Res, 2003,63 ( 3 ) : 713- 722.
1Jelsch M, Kaipainen A, Joukov V, et al. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice[J]. Science, 1997,276:1423.
2Bunone G, Vigneri P, Mariani L, et al. Expression of angiogenesis stimulators and inhabitors in human thyroid tumors and correlation with clinicalpathological features [J]. American Journal of Pathology, 1999,155(6) :1967- 1976.
3Joukov V, Kumar V, Sorsa T, et al. A recombinant mutant vascular endothelial growth factor-C that has lost vascular endothelial growth factor receptor-2 binding, activation, and vascular permeability aellvitios [J].Journal of Biochemistry, 1998,273(12) :6599 - 6602.
4Masatsugu U, Yoshito Y, Koji K, et al. Correlation between vascular endothelial growth factor-C expression and invasion phenotype in cervical carcinomas [J]. International Journal of Cancer, 2002,98:335 - 343.
5Makinen T;Jussila L;Veikkola T.Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor 3[J],2001(02).
6Hornig C;Welch HA;Jeanette MW.Soluble VEGF receptor recombinant and naturally occurring forms involved in the regulation of angiogenesis[J],1999(01).
7Migdal M;Huppertz B;Tessler S.Neuropilin-1 is a placenta growth factor-2 receptor[J],1998(35).
8Hamada T;Ui-Tei K;Miyata Y.A novel gene derived from developing spinal cords SCDGF,is a unique member of the PDGF/VEGF family[J],2000(02).
9Brekken RA;Overholser JP;Stastny VA.Selective inhibition of vascular endothelial growth factor(VEGF)receptor 2 (KDR/FIk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice,2000(18).
