异丙酚MAC技术应用于肠镜检查和治疗的评价

Clinical research on propofol MAC applied to colonoscopy and therapy

目的分析肠镜检查治疗中应用异丙酚进行监测麻醉(monitored anesthesia care,MAC)的价值和意义。方法100例肠镜检查患者分为两组:对照组(n=50)按常规进行肠镜检查,MAC组(n=50),给予异丙酚2.0mg/kg后进行肠镜检查,比较两组患者(1)检查前、中、后,血压、心率及血氧饱和度的变化;(2)腹胀、腹痛发生率及不良感受发生率;(3)肠镜操作时间。结果MAC组检查中血压、心率及血氧饱和度平稳,而对照组中血压、心率有不同程度升高;两组均无并发症发生。MAC组对肠镜检查过程无记忆及不良感受,其肠镜操作时间与对照组相比明显缩短(P<0.01)。结论异丙酚应用于肠镜检查安全、有效,无痛肠镜值得临床推广。

Objective To research the feasibility and safety of application of propofol undergoing monitored anesthesia care （MAC） during cotonoscopy. Methods 100 cases with colonoscopy were divided into two groups. Conlrol group（50 cases） were car ried on eolonoseopy without MAC,MAC group（50 cases） were given intravenous injection propofol with the dose of 2.0mg/kg. Comparing（1）the poor reaction of the patient and the changes of BP, ttR and SpO2 in MAC group and control group. （2）Patient＇s calm state（BERGGEREN ）,the poor reaction and the changes of BP,HR,R and SpO2 in every group. Results In MAC group; 100% of the patient reached 4 grades of calm states,BP, HR and SpO2 were steady during colonoscopy procedures. There was no complication to take place in all experiment groups,and no memory or poor feeling during colonoseopy procedures. In MAC group, profofol influencing breath and circulation was smaller. Conclusion Propofol is applied to colonoscopy safely and effectively.