摘要
目的:探讨乙二胺四乙酸铁钠(NaFeEDTA)口服液治疗婴幼儿缺铁性贫血的疗效及其对血清微量元素的影响。方法:对101例缺铁性贫血(IDA)患儿给予NaFeEDTA口服液0.5mg·kg-1·d-1,连服8周,治疗前、后分别测定血常规和微量元素,并与正常儿童进行对照。结果:用药8周后93.0%的IDA患儿血红蛋白(Hb)恢复至正常水平(P<0.01);治疗前IDA患儿血清铁、锌、铜均较正常儿童低(P<0.05),治疗8周后血清铁、锌、铜均较治疗前明显升高(P<0.05),血清钙、镁变化不明显。结论:NaFeEDTA口服液治疗婴幼儿IDA临床效果好,可显著升高血清铁、锌、铜水平。
Objective : To explore the effects of NaFeEDTA liquid on the treatment of iron deficiency anemia and the levels of trace elements in serum in children. Methods: 101 children with iron - deficiency anemia were treated with NaFeEDTA liquid for 8 weeks, 0. 5mg·kg^-1·d^-1. The levels of trace elements in serum and routine analysis of blood were detected before and after treatment and compared to healthy children. Results: The recovery rate of hemoglobin was 93 % after treatment ( P 〈 0. 01 ) . Before treatment the levels of serum iron, zinc and copper were lower than those in the healthy children ( P 〈 0. 05 ) . The levels of serum iron, zinc and copper after treatment were significantly higher than those before treatment ( P 〈 0. 05 ) , NaFeEDTA liquid had no effect on serum levels of calcium and magnesium. Conclusion: The effect of NaFeEDTA liquid is prominent, which can increase the levels of serum iron, zinc and copper remarkably.
出处
《中国妇幼保健》
CAS
北大核心
2009年第6期848-849,共2页
Maternal and Child Health Care of China
基金
河北省科学技术研究与发展第一批指导计划立项课题〔课题编号:05276413〕