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胰胆管合流异常对肝脏损伤作用的实验研究 被引量:2

The experimental study of hepatic injuries induced by anomalous pancreaticobiliary ductal union
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摘要 胰胆管合流异常(APBDU)是胰管和胆管在十二指肠壁外汇合,形成共同通道过长,十二指肠乳头部括约肌的作用不能影响整个合流部位,胆汁、胰液互流而引起的胆道、肝脏和胰腺疾病。自APBDU这—概念提出以来,人们进行了大量研究,但其发生的病因学机制尚未完全阐明,其与急性胰腺炎、胆道癌、胆管扩张等疾病的因果关系,也仍是进一步深入研究的课题。关于APBDU时胆道和胰腺损伤的报道有很多,我们建立APBDU的实验动物模型来研究肝脏的损伤。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2009年第3期231-232,共2页 Chinese Journal of Hepatology
基金 江苏省“135”工程重点人才项目(2003098)
关键词 模型 动物 线粒体肿胀 丙二醛 胰胆管合流异常 肝脏损伤 Models, animal Mitochondrial swelling Malondialdehyde Anomalous panereatieobiliary ductal union Hepatic injury
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