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热休克蛋白70的胃肠黏膜分子伴侣保护作用及免疫调节功能 被引量：6

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摘要 热休克蛋白(heat shock protein,HSP)是机体细胞在热应激或其他应激状态下合成增多的一类蛋白质,在细胞的多种功能中具有十分重要的作用。文章主要综述热休克蛋白70作为细胞内保护者在胃肠黏膜对抗细胞毒素和细胞应激中所发挥的"分子伴侣"功能及细胞外HSP70作为免疫系统的"危险信号"的免疫调节功能,以便更好地了解细胞保护和细胞修复机制,为炎性胃肠疾病、肿瘤及自身免疫性疾病等提供新的治疗策略。
作者 丁志辉 张红艳
机构地区 南昌大学研究生院医学部 南昌大学第一附属医院烧伤外科
出处 《江西医学院学报》 CAS 2009年第1期136-138,共3页 Acta Academiae Medicinae Jiangxi
关键词 热休克蛋白70 分子伴侣 胃肠道保护 免疫调节
分类号 R57 [医药卫生—消化系统]
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参考文献34

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二级参考文献26

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二级引证文献15

江西医学院学报
2009年 第1期

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