非霍奇金淋巴瘤患者化疗后继发急性早幼粒细胞白血病一例并文献复习
摘要
患者 女,20岁,因“发现淋巴结肿大半个月”于2006年2月14日入院,当时无意中发现颈部及腹股沟淋巴结肿大,约2cm×2cm大小,活动,光滑,无压痛,未伴发热、食欲不振、盗汗,消瘦,到南阳市肿瘤医院就诊,行腹股沟淋巴结活组织检查,切除淋巴结送河南省肿瘤医院行病理检查,
出处
《白血病.淋巴瘤》
CAS
2009年第3期191-192,共2页
Journal of Leukemia & Lymphoma
参考文献14
-
1Grimwade D, Walker H, Oliver F, et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1612 patients entered into the MRC AML 10 trial. The Medical Resarch Council Adult and Children's Leukemia Working Parties. Blood, 1998, 92: 2322-2333.
-
2Smith SM, Le Beau MM, Huo D, et al. Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series. Blood, 2003, 102: 43-52.
-
3Fortune JM, Osheroff N. Topoisomerase Ⅱ as a target for anticancer drugs: when enzymes stop being nice. Prog Nucleic Acid Res Mol Biol, 2000, 64: 221-253.
-
4Negrini M, Felix CA, Martin C, et al. Potential topoisomerase Ⅱ DNA-binding sites at the breakpoints of a t (9;11) chromosome translocation in acute myeloid leukemia. Cancer Res, 1993, 53: 4489-4492.
-
5Ahuja HG, Felix CA, Aplan PD. Potential role for DNA topoisomerase Ⅱ poisons in the generation of t (11;20)(p15;q11) translocations. Genes Chromosomes Cancer, 2000, 29: 96-105.
-
6Domer PH, Head DR, Renganathan N, et al. Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase Ⅱ consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11). Leukemia, 1995, 9: 1305-1312.
-
7Strissel PL, Strick R, Rowley JD, et al. An in vivo topoisomerase Ⅱ cleavage site and a DNase Ⅰ hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region. Blood, 1998, 92: 3793- 3803.
-
8Zhang Y, Strissel P, Strick R, et al. Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase Ⅱ DNA cleavage and DNase Ⅰ hypersensitive sites in t(8;21) leukemia. Proc Natl Acad Sci U S A, 2002, 99: 3070-3075.
-
9Dong S, Geng JP, Tong JH, et al. Breakpoint clusters of the PML gene in acute promyelocytic leukemia: primary structure of the reciprocal products of the PML-RARα gene in a patient with t(15; 17). Genes Chromosomes Cancer, 1993, 6: 133-139.
-
10Mistry AR, Felix CA, Whitmarsh R J, et al. DNA topoisomerase Ⅱ in therapy-related acute promyelocytic leukemia. N Engl J Med, 2005, 352: 1529-1538.
-
1胡静,钱晓萍,刘宝瑞,臧秦川.拓扑异构酶与肿瘤多药耐药及耐药逆转[J].国外医学(肿瘤学分册),2005,32(2):110-113. 被引量:5
-
2董苑,朱易凡,李松奇.乳腺癌新辅助化疗对拓扑异构酶Ⅱα表达的影响[J].中华普通外科学文献(电子版),2009,3(5):31-33. 被引量:3
-
3高显华,于志奇,张畅,傅传刚,徐晓东,邢俊杰.拓扑异构酶Ⅱα在结直肠癌组织中的表达及其临床意义[J].国际外科学杂志,2012,39(8):522-525. 被引量:2
-
4程琳,郑海军,岳树春,张振忠,薄爱华.检测膀胱癌TopoⅡα和MT对指导化疗药物的选择价值[J].陕西医学杂志,2007,36(1):47-48. 被引量:1
-
5许建林,姜楠,杨国山.拓扑异构酶、增殖细胞核抗原及p53在结直肠癌中的表达及其临床病理意义[J].中华临床医师杂志(电子版),2012,6(17):5083-5086. 被引量:1
-
6傅兴宁,孔庆暖,黄维清,卫红军,王海燕,陈桦.肺癌组织P-gp、GST-Ⅱ和TOPO-Ⅱ表达及与Ki-67相关性[J].齐鲁医学杂志,2013,28(1):11-13. 被引量:6
-
7杨良权,娄欢欢,周东光,李明雷.不同分子分型乳腺癌新辅助化疗对TopⅡα蛋白表达的影响[J].河北医科大学学报,2017,38(2):230-233. 被引量:3
-
8王晓文,杨亮,朱丽萍,倪多,艾司克尔·阿尤甫.Ki-67及TopoⅡ在三阴乳腺癌中的表达及意义[J].中国普通外科杂志,2014,23(5):692-694. 被引量:2
-
9黄颖,陈小岩.肾癌组织中P-gp、TopoⅡ、GST-π及ki67、p53表达的临床病理意义[J].福建医科大学学报,2003,37(S1):77-79.
-
10魏若晶,贾宁,杨文增,周洪月,赵春利,张彦桥.膀胱癌组织中拓扑异构酶Ⅱ的表达及意义[J].军医进修学院学报,2008,29(4):337-338.