3-(2-丁烯酰基)-2-口恶唑烷酮的不对称催化Diels-Alder反应

Synthesis of 2-(±)-[(4-fluoro phenyl)methoxy] Propanoic Acid and its Derivatives

报道了在手性配体（２Ｒ，３Ｒ）－（－）－１，１，４，４－四－（１－萘基）－２，３－（缩丙酮）－１，４－丁二醇与ＴｉＢｒ２（ｉ－ＯＰｒ）２作用制得的催化剂存在下，３－（２－丁烯酰基）－２－唑烷酮与环戊二烯的不对称催化Ｄｉｅｌｓ－Ａｌｄｅｒ反应．并对该反应机理作了初步的解释．

The 2-(±)-[(4-fluoro phenyl)methoxy]propanoic acid and its derivatives (5～10)were prepared from 4-amino-1-methyl benzene in order to compare structure-activity relationships with [(4-fluoro phenyl)methoxy]acetic acid and its derivatives.Sixth new compounds 5～10,the structures of which were ascertained by NMR,IR spectra and elementary analysis,were presented in this paper.