蒲皂愈炎汤治疗湿热瘀毒蕴结之慢性盆腔炎163例临床观察

Treatment of 163 CPI Cases of Damp-heat Toxin Brewing and Binding with Pu Zao Inflammation-Healing Decoction

目的:对蒲皂愈炎汤治疗慢性盆腔炎(湿热瘀毒蕴结证)的临床疗效和安全性做出评价。方法:采用随机、阳性药平行对照的临床研究方法,以奥硝唑作为对照药。共观察325例(1:1),其中蒲皂愈炎汤组163例,奥硝唑组162例。结果:蒲皂愈炎汤能有效地改善慢性盆腔炎患者的各项中医症状(P<0.01)。蒲皂愈炎汤组中医症状疗效、局部体征疗效明显优于奥硝唑组(P<0.05),患者下腹胀痛、刺痛,腰骶胀痛,带下色黄等症状的改善明显优于奥硝唑组(P<0.01),其局部体征积分高于奥硝唑组(P<0.01)。结论:蒲皂愈炎汤治疗慢性盆腔炎(湿热瘀毒蕴结证)疗效确切,未发现明显的副反应。

Objective：To evaluate the clinical effectiveness and safety of Pu Zao Inflammation-Healing Decoction for the treatment of chronic pelvic inflammation （CPI） of pattern of Damp-heat Toxin Brewing and Binding. Methods：Through the Methods of randomization and using of ornidazole as the positive control drug, 325 patients were observed （163 cases treated with the decoction, 162 cases with ornidazole）. Results： The decoction is effective for relieving various symptoms of Chinese medicine （ P 〈 0. 01 ） ; compared with ornidazole, the decoction alleviated the symptoms of lower-abdomen distending and stabbing pain, lumbosacral distending pain, and yellow ]eukorrhea more effectively （ P 〈 0. 05 ） , meanwhile, it scored higher in local physical signs scale （ P 〈 0. Ol ）. Conclusion： Pu Zao Inflammation-Healing Decoction has confirmed curative effect and rare side effect for chronic pelvic inflammation of pattern of Dampheat Toxin Brewing and Binding.