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基质金属蛋白酶-1基因多态性与心肌梗死发病的关系研究 被引量:1

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摘要 冠心病所致的心肌梗死多发生于冠状动脉轻、中度狭窄患者中.导致其发生的主要原因是动脉粥样硬化斑块破裂和血栓形成。前者与斑块的易损性密不可分。大量研究发现易损斑块与基质金属蛋白酶(MMPs)有关。MMP-1是MMPs家族重要的一员,MMP-1的表达及活性增强与冠心病的发生、发展密切相关。
出处 《中国药物与临床》 CAS 2009年第3期204-206,共3页 Chinese Remedies & Clinics
基金 山西省高等学校科技研究开发项目(200811075)
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