含三聚氰胺奶粉致婴幼儿泌尿系统损伤282例的临床分析

Analysis of urinary system injury in 282 infants feeded by milk powder containing melamine

目的:鉴于三聚氰胺奶粉事件引起的广泛关注,分析三聚氰胺奶粉致婴幼儿泌尿系统损伤的情况。方法:对因服用含三聚氰胺奶粉的2032例就诊婴幼儿进行尿常规、尿沉渣和肾B超检查。结果:2032例中存在泌尿系统损伤282例,阳性检出率为13.9%。其中血尿140例(占6.9%);B超下单侧或双侧肾脏有结晶的60例(占2.9%);肾盂积水或输尿管扩张的35例(占1.7%);血尿伴单侧或双侧肾脏结晶的23例(占1.1%);血尿伴肾盂积水或输尿管扩张的14例(占0.7%);单侧或双侧肾脏结晶伴积水的10例(占0.5%)。结论:长时间服用含三聚氰胺的奶粉可导致镜下血尿、肾盂积水或输尿管扩张,甚至引起肾功能异常。

Objective： The melamine in milk powder caused wide attention. The mechanism of kidney injury in infants caused by the milk powder containing melamine is explored. Methods：We checked the urine test, urine sediment and kidney ultrasonic B routinely for 2032 patients taking the milk powder containing melamine. Results：The total incidence of injury in urinary system was 13.9% （282 cases）. Hematuria was found in 140 patients, accounting for 6.9% of all the patients. The renal ultra-B detection indicated that 60 paients had unilateral or bilateral renal crystallization, accounting for 2.9% of all the patients, 35 paients had hydronephrosis or ureter expansion, accounting for 1.7% of all the patients. 23 patients showed hematuria with unilateral or bilateral renal crystallization, accounting for 1.1% of all the patients. 14 patients showed hematuria with hydronephrosis or ureter expansion, accounting for 0.7% of all the patients. 10 patients showed unilateral or bilateral renal crystallization and hydronephrosis, accounting for 0.5% of all the patients. Conclusion：Long-term feeding of the milk powder containing melamine may cause urine red cell, hydronephrosis or ureter expansion, even renal dysfunction.