摘要
目的研究人工培养云南本土冬虫夏草菌粉(YNCS)在ICR小鼠体内的抗炎效果.方法ICR小鼠随机分组,每日用不同剂量的YNCS灌胃,观察YNCS对二甲苯致小鼠耳廓肿胀的影响和对小鼠腹腔毛细血管通透性的影响,以判断YNCS的抗炎效果.结果YNCS低、中、高剂量对二甲苯所致的小鼠耳廓肿胀有显著抑制作用(P<0.05),但对小鼠腹腔毛细血管通透性影响不明显.结论YNCS具有一定抑制肿胀的抗炎效果.
Objective To study the anti-inflammatory effects of cultured Yunnan Cordyceps sinensis （YNCS） in ICR mice. Methods Different dosages of YNCS were intragastriced to ICR mice every day which were randomly divided into several groups. The YNCS effect were observed in swelling of mouse pinnea caused by dimethylbenzene and capillary vessel penetrating experiment, in order to study YNCS anti-inflammatory effects. Results Various doses of YNCS inhibited the swelling of mouse pinnea degree of ICR mice （P 〈 0.05） , but YNCS had no significant effect on capillary vessel penetrating. Conclusion YNCS has anti-inflammation effects to some extent.
出处
《昆明医学院学报》
2009年第2期36-39,共4页
Journal of Kunming Medical College
基金
云南省教育厅基金资助项目(07C41064)
关键词
冬虫夏草
抗炎
ICR小鼠
云南
Cordyceps Sinensison
Anti-inflammation
ICR mouse
Yunnan
