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实验动物兔子心电图奇异性检测:进化谱方法 被引量：1

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摘要 基于小波变换的进化谱分析能够揭示非平稳信号特定时刻的时—频域特性.实验动物兔子左冠状动脉前降支结扎实验,可以模拟早期心肌缺血症状的不同生理变化过程.左冠状动脉病变引发心肌缺血是急性心肌梗死等冠心病的早期主要征兆.文中提出了基于连续复小波变换的进化谱估计算法,在满足时—频域不确定性原理条件下,为获得非平稳信号的瞬时频谱提供了一种有效的新方法,它能够识别生命系统数据中的局部奇异性.应用这种算法对实验动物兔子的多种心电图数据的进化谱分析结果表明,QRS波群进化谱特性的变化与早期心肌缺血有内在关联.QRS波群进化谱品质因数Q是心电图在时—频域的一个特征参数,Q数值变异可能为识别早期心肌缺血提供一种新的医学诊断参考特征.
作者 刘新元 何定武 裴留庆
机构地区 北京大学信息科学技术学院 北京师范大学信息科学与技术学院
出处 《自然科学进展》 北大核心 2009年第4期446-455,共10页
基金 国家自然科学基金资助项目(批准号:607710003)
关键词 非平稳信号 心电图(ECG) 进化谱 瞬时频谱 心肌缺血
分类号 TP206.3 [自动化与计算机技术—检测技术与自动化装置] Q95-331 [生物学—动物学]
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参考文献11

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同被引文献14

  • 1刘新元,谢柏青,戴远东,王福仁,李壮志,马平,谢飞翔,杨涛,聂瑞娟.射频SQUID心磁图数据自适应滤波研究[J].物理学报,2005,54(4):1937-1942. 被引量：3
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  • 4Cohen D, Edelsack E A, Zimmerman J E. Magnetocardiograms taken inside a shielded room with superconduction point-contact magnetometer. Appl Phys Lett, 1970, 16:278.
  • 5Karsten S, Alex I. Braginski, biomagnetism using SQUIDs: Status and perspectives. Supercond Sci Technol, 2006, 19:160--170.
  • 6Pola A, Macerata A, Emdin M. Estimation of the power spectral in nonstationary cardiovascular time series: Assessing the role of the time-frequency representations (TFR). IEEE Trans Biomed Eng, 1996, 43:46-59.
  • 7Friedman B H, Allen M T, Christie I C, et al. Validity concerns of common heart-rate variability indices addressing quantification issues in time-and frequency-domain measures of HRV. IEEE Eng Med Biol, 2002, 21:35--40.
  • 8Priestley M B. Wavelets and time-dependent spectral analysis. J Time Series Analysis, 1996, 17:851--03.
  • 9Kosch O, Meindl P, Steinhoff U, et al. Physical aspects of cardiac magnetic fields and electric potentials. In: The 12th International Conference on Biomagnetism, 2000, August 13- 17, Helsinki, Finland.
  • 10Goernig M, Liehr M, Tute C, et al. Magnetocardiography based spatiotemporal correlation analysis is superior to conventional ECG analysis for identifying myocardial injury. Inter J Bioelectromagne, 2009, 11: 107--111.

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自然科学进展
2009年 第4期

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