成都市健康体检人群乙型肝炎血清流行病学研究

A Seroepidemiologic Study on Hepatitis B among Population of Health Examination in Chengdu

目的:探讨成都市健康体检人群乙型肝炎病毒血清流行病学状况,并为乙型病毒性肝炎防治提供可靠依据。方法:收集2007年6月至2007年12月成都市体检人群共计10112人,分别统计年龄、性别、乙型肝炎"两对半"结果和肝功能。结果:成都市健康体检人群HBsAg阳性率为4.62%,男性和女性HBsAg阳性率分别为6.0%和2.96%,男性明显高于女性;乙型肝炎病毒感染者中HBeAg阳性和HBeAg阴性分别占16.1%和83.9%;抗-HBs阳性率为56.94%,乙型肝炎标志物全阴为36.17%。结论:成都市健康体检人群HBsAg阳性率明显低于全国平均水平;乙型肝炎病毒感染者中HBeAg阴性占83.9%。

Objective：To explore the serological infection rate of hepatitis B virus（HBV）among population of health examination in Chengdu and to provide information for control and prevention of the disease. Methods： The data including age, sex, hepatitis B virus markers and liver function were recorded in detail among 10112 cases of heahh examination in Chengdu from June to December 2007. Results：The prevalence rates of HBsAg and anti-HBs were 4.62 % and 56.94% respectively. The positive rates of HBsAg among men was higher than women,6.0% and 2.96% respectively. HBeAg-positive and HBeAg-negative were 16. 1% and 83. 9% respectively. The negative rate of hepatitis B virus markers was 36.17% among all population of health examination. Conclusion： The prevalence rate of HBsAg among population of health examination in Chengdu was lower than national average lever. HBeAg-negative was 83. 9% in HBV infection.