宫颈微小偏离性腺癌临床病理分析(附8例报告)

A Clinicopathological Analysis of Minimal Deviation Adenocarcinoma of the Uterine Cervix:Report of 8 Cases

目的:探讨宫颈微小偏离性腺癌的诊断与治疗。方法:按照WHO(2003)宫颈腺癌分类标准,回顾性分析我院收治的8例宫颈微小偏离性腺癌的临床病理资料。结果:宫颈微小偏离性腺癌占同期收治宫颈浸润腺癌的4.73%,临床表现为水样白带和/或生殖道出血、宫颈肥大变硬和赘生物,阴道B超检查示宫腔积液,宫颈细胞学诊断较困难,常需深部活检组织诊断。结论:诊断应结合临床表现,影像学检查,宫颈细胞学。当高度怀疑时应取深部组织或宫颈锥切组织诊断,早期诊治预后较好。

Objective：To investigate the diagnosis and therapy of the minimal deviation adenocarcinoma（MDA）of the uterine cervix. Methods：The clinical and pathologic materials of 8 cases with MDA of the uterine cervix treated in our hospital were analyzed retrospectively. The pathologic classification was performed in accordance with WHO（2003）classification criteria for cervical adenocarcinoma. Results：Cervical MDA accounts for 4.73% （8/169） of invasive cervical adenocarcinoma of the same period. The clinical symptome is watery vaginal discharge and/or reproductive tract hemorrhage,cervical hypertrophy or neoplastic lesion. And transvaginal sonography observes intrauterine fluid accumulation. Cervical cytology is usually hard to confirm a diagnosis and the deep tissue biopsy is necessary to make. Conclusion：The diagnosis of MDA should depend on the combination of clinical manifestations,imaging examination and cytology. When MDA is of high clinical implication, a deep biopsy or cervical conization is necessary to make an accurate diagnosis. Early detection and operation get the better prognosis.