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杭州市1995~2006年健康人群百日咳 白喉 破伤风抗体水平监测分析 被引量:11

Observation of Immunity Level of Pertussis-Diphtheria-Tetanus in Healthy People in Hangzhou City during 1995-2006
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摘要 目的了解杭州市健康人群百日咳、白喉、破伤风抗体水平。方法1995~2006年,在不同区(县、市),分2~4岁、6~8岁、13~15岁、25~39岁4个年龄组开展百日咳、白喉、破伤风抗体监测。结果百日咳抗体共监测1942人,保护率为93.87%,几何平均摘度为1∶1037.36。其中农村2~4岁保护率低于其它三个年龄组,与6~8岁、13~15岁组保护率差异有非常显著的统计学意义(χ2=8.80、6.13;P均<0.01)。白喉抗体监测2141人,阳性率91.59%,几何平均浓度(GMC)为0.291国际单位/毫升(IU/ml)。破伤风抗体监测2141人,阳性率72.35%,GMC为0.095IU/ml。结论应加强农村地区的免疫规划管理及预防接种工作。 Objective To study the pertussis-diphtheria-tetanus immunity level of healthy people in Hangzhou. Methods Pertussis antibody, diphtheria antitoxin and tetanus antitoxin were tested. We carried out surveillance in different counties among the people at 2-- 4,6-- 8,13-- 15, 25--39 age group during 1995--2006. Results It showed that the pertussis antibody positive rate of 1942 persons was 93.87% ,GMT 1 : 1037. 36 IU/ml,the antibody of people in countryside for the people at 2--4 age group was lower than that of other groups and the difference was significant compared with 6 -- 8,13 - 15 age group (χ^2 = 8.80,6.13, P 〈 0.01 ). The diphtheria antitoxin positive rate of 2141 persons was 91.59%,with the GMT was 0. 2911IU/ml. The tetanus antitoxin positive rate of 2141 persons was 72.35% ,GMT 0. 095IU/ml. Conclusions We need to strengthen the EPI work in rural areas.
出处 《中国疫苗和免疫》 CAS 2009年第1期68-71,共4页 Chinese Journal of Vaccines and Immunization
关键词 百日咳抗体 白喉抗体 破伤风抗体 监测 Pertussis antibody Diphtheria antitoxin Tetanus antitoxin Surveillance
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