摘要
目的探讨泮托拉唑联合洁维乐治疗消化性溃疡的疗效及安全性。方法运用随机配对方法将291例消化性溃疡患者分成试验组和对照组2组,分别为A组(试验组)155例,口服泮托拉唑40mg,每日1次,洁维乐20g,每日3次;B组(对照组)136例,口服泮托拉唑40mg,每日1次,复方维U颠茄铋铝片2片,每日3次。上述患者同时接受抗HP治疗。胃镜观察溃疡愈合情况。结果6周后,A组患者总有效率为94.2%,B组总有效率为69.9%。两组间差异有显著性(P〈0.05)。结论针对消化性溃疡愈合及HP根除而言,泮托拉唑联合洁维乐疗效优于泮托拉唑联合复方维u颠茄铋铝片,且不良反应少。
Aims: To evaluate the efficacy and safety of Pantoprazole United Colloidal Aluminium Phosphate Gel in treating adults with peptic ulcer.Methods: 291 patients with peptic ulcer were randomly assigned to test team and control group.A group, 155 patients to receive Pantoprazole 40mg qd, Colloidal Aluminium Phosphate Gel 20g tid; B group, 136 patients to receive Pantoprazole 40mg qd, Compound Vitamin U and Bismuth Subcarborate Tablets 2 Tablets tid.All the patients accept anti-hp therapy at the same time.Endoscopies were performed before and after the treatment.Results: After 6 weeks, A group of patients with total effective rate was 94.2%, B group, the total efficiency of 69.9% .The significant differences were observed between two ground (P〈0.05) .Conclusions: On peptic ulcer healing and eradication of Helicobacter pylori, Combined with Pantoprazole and Colloidal Aluminium Phosphate Gel was more effective than Combined with Pantoprazole and Compound Vitamin U and Bismuth Subcarborate Tablets, and less adverse reactions.
关键词
消化性溃疡
泮托拉唑
洁维乐
peptic ulcer
Pantoprazole
Colloidal Aluminium Phosphate Gel