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慢性前列腺炎患者前列腺液中MIP-2、iNOS的表达变化及意义 被引量:2

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摘要 目的观察不同类型慢性前列腺炎患者前列腺液(EPS)中巨噬细胞炎性蛋白-2(MIP-2)、诱导型一氧化氮合酶(iNOS)的表达变化,并探讨其临床意义。方法45例慢性前列腺炎患者,分为慢性细菌性前列腺炎(CBP)组、慢性非细菌性前列腺炎/慢性骨盆疼痛综合征(CPPSⅢA)组和慢性非细菌性前列腺炎/慢性骨疼痛综合征(CPPSⅢB)组3组。用ELISA法、光化学法分别对患者及正常对照组EPS中MIP-2、iNOS进行检测。结果CBP组、CPPSⅢA组、CPPSⅢB组、对照组患者EPS中MIP-2分别为(12.79±1.65)、(10.83±1.04)、(8.46±1.10)、(7.21±0.49)ng/ml,组间两两比较,P均<0.05。CBP组、CPPSⅢA组、CPPSⅢB组、对照组患者EPS中iNOS水平分别为(32.67±4.24)、(28.32±4.36)、(21.04±4.14)、(16.06±2.10)ng/ml,组间两两比较,P均<0.05。结论慢性前列腺炎患者EPS中的MIP-2、iNOS水平升高,二者可作为诊断慢性前列腺炎有价值的指标。
出处 《山东医药》 CAS 北大核心 2009年第6期71-72,共2页 Shandong Medical Journal
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  • 1Chamness SL. The effect of androgen on NOS in the male reproductive tract of the rat. Fertil Steril, 1995,63 : 1101.
  • 2Guh JH. Antiproliferative effect in human prostatic mooth muscle cells by nitric oxide donor. Mol Pharmacol, 1998 , 53:467-474.
  • 3Roberts RO,Lieber MM,Bostwick DG,et al.A review of clinical and pathologyical prostatitis syndromes.Urology,1997,49:809 -821.
  • 4Nadler RB,Koch AE,Colhoun EA,et al.IL-β and TNF-α in prostatic secretions are indicators in the evaluation of men with chronic prostatitis.J Urol,2000,164:214-218.
  • 5Miller LJ,Fischer KA,Goralinick SJ,et al.Interleukin-10 levels in seminal plasma:implications for chronic prostatitis-chronic pelvic pain syndrome.J Urol,2002,167:753-756.
  • 6Nickel JC.Prostatitis:myths and realities.Urology 1998 Mar,51(3):362 -366.
  • 7Harris MT,Fdldberg RS,Lau KM.et al.Expression of proinflammatory genes during estrogen-induced inflammation of rat prostate.Prostase 2000 Jun 15,44(1):19-25.
  • 8Nickel JC,Effective office management of chronic prostatitis.Urol Clin North Am,1998,25 (4):677-84.
  • 9Mukaida HA,Matsushima K.Interleukin-8 (IL-8) and monocyte chemotactic and activating facter (Mcaf/Mcp),chemokines essentially involed in inflammation and immune reactions[J].Cytokine & Growth Factor Reviews,1998,9:9-23.
  • 10Nickel JC.Prostatitis:Evolving management strategies.Urol Clin North Am,1999,26 (4),737-751.

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