头针配合药物对急性脑梗死患者血清MDA的影响

Observations on the Influence of Skull Acupuncture Plus Medication on Serum MDA in Acute Cerebral Infarction Patients

目的探讨针刺颅骨缝区(头针)对急性脑梗死(CI)痰证患者血清丙二醛(MDA)的影响。方法分别采用针刺颅骨缝区(冠状缝、矢状缝、人字缝等)加药物(B组)和单纯药物(A组)治疗急性CI痰证患者各20例,对照观察患者血清MDA含量变化。结果治疗前后A组血清MDA含量变化无显著性差异(P>0.05),B组血清MDA含量降低差异显著(P<0.01),治疗后B组血清MDA水平与A组比较差异有统计学意义(P<0.05);A、B两组治疗前后临床神经功能缺损评分值差异显著(P<0.05,P<0.01),B组较A组更明显地降低临床神经功能缺损评分值(P<0.05)。结论头针加药物治疗急性脑梗死痰证患者比单纯药物治疗,能更有效降低血清丙二醛的含量,降低神经功能缺损评分值。

Objective To investigate the influence of acupuncture at cranial suture areas （skull acupuncture） on serum malondialdehyde （MDA） in acute cerebral infarction （CI） patients with phlegm syndrome. Methods Twenty acute CI patients with phlegm syndrome were treated with acupuncture at cranial suture areas （coronal suture, sagittal suture and lambdoid suture） plus medication （group B） and 20 cases of the same condition, with simple medication （group A）. Serum MDA contents were compare between pre- and post-treatment and between the two groups. Results There was no significant difference in serum MDA content between pre- and post-treatment in group A （P〉0.05）. Serum MDA content significantly decreased after treatment in group B （P〈0.01）. There was a significant post-treatment difference in serum MDA levels between group B and group A （P〈0.05）. There was a significant post-treatment difference in clinical neural deficit score in both group A and group B （P〈0.05,P〈0.01）. Clinical neural deficit score decreased significantly more in group B than in group A （P〈0.05）. Conclusion Skull acupuncture plus medication can decrease serum MDA content and neural deficit score more effectively than simple medication in treatment of acute cerebral infarction patients with phlegm syndrome.