近视眼角膜前后表面形态及角膜厚度的相关研究

Corneal topography and pachymetry in myopic eyes

目的:探讨近视患者角膜前后表面形态及角膜厚度之间的相互关系,为临床应用提供参考。方法:应用Orb-scanII眼前节分析系统和超声角膜测厚仪对202例(400眼)近视患者进行检查,测量患者等效球镜度、角膜前后表面曲率半径、屈光力、前突极值及角膜厚度。各参数之间进行Pearson相关性分析。结果:患者角膜厚度与等效球镜度成负相关(P<0.01),与角膜后表面各参数之间有相关性(P<0.05),与角膜前表面各参数之间并无相关性(P>0.05);角膜前后表面曲率半径之间成显著正相关(r=0.901,P<0.01),但前突极值之间并无相关性(P>0.05),角膜前表面曲率半径与角膜后表面屈光力成负相关(P<0.01),角膜后表面曲率半径与角膜前表面高度值成负相关(P<0.01)。结论:近视眼患者近视程度越大,角膜越薄;通过角膜厚度可以推测角膜后表面形态;角膜厚度或许会成为临床筛查早期圆锥角膜的指标之一。

Objective： To explore the relationships between corneal topography and pachymetry on myopic eyes. Methods： The Orbscan Ⅱ and ultrasonic corneal pachymeter were used, include 400 myopic subjects. Corneal anterior and posterior surface curvature radius, diopter, elevation and corneal thickness were recorded. Pearson analysis was used to reveal the relationships among these values. Results： There was a negative correlation between the equivalent diopter and corneal thickness （P〈0.01）in patients with myopic eyes;the cornea thickness had correlations with the values of corneal posterior surface （P〈0.05）, but had no correlation with anterior surface （P〉0.05）; there was a significant positive correlation between the corneal anterior and posterior surface curvature radius （P〈0.01）, and no correlation between the corneal anterior and posterior surface elevation （P〉0.05）;There was a negative correlation between the corneal anterior surface curvature radius and posterior surface diopter, the corneal posterior curvature radius and anterior elevation （P〈0.01）. Conclusion： The higher the degree of myopia, the cornea thinner. Perhaps we can speculate the cornea posterior surface patterns by the thickness.