女性生殖道支原体感染及其耐药性分析

Analysis on Mycoplasma Infection and Its Drug Resistance in Female Reproductive Tract

目的探讨女性生殖道支原体感染及耐药情况。方法应用支原体培养试剂盒对江阴市人民医院妇科、皮肤科患者生殖道分泌物进行检测,对支原体培养阳性者进行耐药性试验。结果222例女性生殖道支原体感染阳性率为45.0%,其中解脲支原体(UU)阳性占91.0%,人型支原体(MH)阳性占2.0%,UU-MH阳性占7.0%,91例UU感染者对美满霉素、强力霉素、克拉霉素耐药性较低。结论该地区女性生殖道支原体感染宜用美满霉素、强力霉素、克拉霉素治疗,支原体培养和药敏试验结果有助于指导临床合理用药。

[ Objective ] To investigate the status of mycoplasma infection and its drug resistance in female reproductive tract. [ Methods] The secretions in reproductive tract of patients in gynecology and dermatology of Jiangyin People＇s Hospital were detected with special agent kit, and drug resistance test was carried out in mycoplasma positive cases. [ Results] The positive rate of mycoplasma in female reproductive tract was 45.0%. It contained the positive rate of ureaplasma urealytieum （ UU ） accounted for 91.0% ,that of mycoplasma hominis（MH） accounted for 2.0%, that of both UU and MH accounted for 7.0%. The drug resistance of 91 UU infection cases to minocycline, doxycycline and clarithromycin was lower. [ Conclusion] Minocycline, doxycycline and clarithremycin are effective in the treatment of mycoplasma infection in female reproductive tract in this area. The results of mycoplasma culture and drug resistance test are helpful to guide the reasonable utilization of drug in clinic.