颈动脉超声预测冠心病的应用价值

Application Value of Carotid Ultrasound in Prediction of Coronary Heart Disease

目的研究冠心病与颈动脉粥样硬化的相关性。方法对205例疑似冠心病的病人行颈动脉的超声及冠状动脉造影检查,按冠状动脉造影结果将患者分为对照组(无冠心病组52例)和总冠心病组(单支病变64例,双支病变48例,3支病变41例)。结果对照组及总冠心病组颈动脉内中膜厚度(IMT)及斑块发生率相比,差异有统计学意义(P<0.01);且冠状动脉单支和多支病变与对照组的颈动脉粥样硬化指标差异均有统计学意义(P<0.01);以IMT≥0.85mm及(或)粥样斑块发生率来预测冠心病的特异性为81.6%,敏感性为75.3%,阳性预测率为71.1%。结论测定颈动脉IMT及粥样硬化斑块的总积分对冠心病的预测诊断具有临床意义。

[ Objective] To study the correlation between carotid atherosclerosis and coronary atherosclerosis heart disease （CHD）. [ Methods] 205 patients with suspected CHD performed carotid artery ultrasonography and coronary angiography. The patients were divided into control group （52 cases of no coronary heart disease） and total coronary heart disease group （64 cases of single vessel lesion, 48 cases of double vessel lesion, 3 cases of triple vessel lesion） [ Results ] Comparing the carotid intima-media thickness （IMT） and plaque incidence between control group and total coronary heart disease group, the differences were significant （P 〈0.01 ） ; The specificity, sensitivity and positive predictive rate for the prediction of CHD was 81.6% ,75.3% ,71.1% respectively, based on IMT≥0.85ram or the incidence of plaque. [ Conclusion] Determination of carotid artery IMT and atherosclerotie plaque total points are significant for predictive diagnosis of coronary heart disease.