交联聚(N-异丙基丙烯酰胺)/(海藻酸钠/聚(N-异丙基丙烯酰胺))半互穿网络水凝胶的制备及其溶胀性能

Preparation and Swelling Properties of Cross-Linked Poly(N-isopropylacrylamide)/(Sodium Alginate/Poly(N-isopropylacrylamide)) Semi-interpenetrating Polymer Network Hydrogel

将线性聚(N-异丙基丙烯酰胺)(PNIPAAm)和海藻酸钠(SA)分子同时引入到PNIPAAm凝胶中,制备了交联聚(N-异丙基丙烯酰胺)/(海藻酸钠/聚(N-异丙基丙烯酰胺))半互穿网络(Cr-PNIPAAm/(SA/PNIPAAm)semi-IPN)水凝胶。在弱碱性条件下(pH=7.4),改变SA与线性PNIPAAm的质量比对Cr-PNIPAAm/(SA/PNIPAAm)semi-IPN水凝胶的溶胀度没有太大的影响。在酸性条件下(pH=1.0),其溶胀度随着SA与线性PNIPAAm质量比的减小而增大。由于亲水性SA与线性PNIPAAm的协同作用,Cr-PNIPAAm/(SA/PNIPAAm)semi-IPN水凝胶的消溶胀速率得到很大提高。

Cross-linked poly （N-isopropylacrylamide）/sodium alginate/linear poly （ N-isopropylacryla- mide） semi-interpenetrating polymer network （Cr-PNIPAAm/（SA/PNIPAAm） semi-IPN） hydrogels were prepared by addition of sodium alginate and linear PNIPAAm into cross-linked PNIPAAm hydrogel net- work. Results indicate that the mass ratios of SA to linear PNIPAAm have little effects on the swelling ratios of Cr-PNIPAAm/（SA/PNIPAArn） semi-IPN hydrogels in weakly alkaline medium （pH = 7. 4）. Whereas the swelling ratios of the hydrogels increase with the reduce of the mass ratios of SA to linear PNIPAAm in strong acidic medium （pH = 1. 0）. Compared with PNIPAAm hydrogels, the deswelling rates of Cr-PNIPAAm/（SA/PNIPAAm） semi-IPN hydrogels are greatly enhanced due to the concurrent effect of the linear PNIPAAm and hydrophilic SA.