摘要
目的研究外伤后癫痫易感性的变化。方法采用自由落体法建立大鼠急性脑外伤模型,描记脑电图,采用戊四氮腹腔注射制备癫痫模型,记录戊四氮最小致痫量。结果大鼠脑外伤后脑电图δ、θ波段较健康大鼠增加,α波减少,δ、θ、α波相对功率值比较有显著性差异(P<0.05);大鼠脑损伤组致痫所需最小戊四氮量值小于健康大鼠对照组(P<0.05)。结论脑外伤后大鼠癫痫易感性增高。
Objective To explore the susceptibility of epilepsy in rat with cerebral trauma. Methods An impact-acceleration head injury model was established with rats. After trauma, the electroencephalograph was recorded. Epileptic model wad established by injecting pentylenetetrazol （PTZ） intraperitoneally and the dosage of PTZ was recorded. Results The wave of delta and theta increased after trauma, alpha and beta decreased and there was significant difference among the power of delta, theta and alpha （P〈 0.05）. The dosage of rats with cerebral trauma was less than that in normal rats （P〈0.05）. Conclusion The susceptibility of epilepsy in rat with cerebral trauma increases.
出处
《中国康复理论与实践》
CSCD
2009年第3期231-232,共2页
Chinese Journal of Rehabilitation Theory and Practice
关键词
脑外伤
癫痫
脑电图
戊四氮
易感性
traumatic brain injury
epilepsy
electroencephalograph （EEG）
pentylenetetrazol （PTZ）
susceptibility
