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小儿小脑星形细胞瘤101例分析 被引量:3

Pediatric Cerebellar Astrocytomas:101 Cases Report
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摘要 目的探讨小儿小脑星形细胞瘤的临床特征、治疗策略和预后。方法回顾性分析101例经病理学证实的小儿星形细胞瘤病例的临床资料,并进行随访。结果男性50例,女性51例,平均年龄9.8岁。肿瘤大小3~7.5cm。实性瘤体型46例,瘤在囊内型24例,囊在瘤内型31例;39例位于小脑蚓部,62例位于小脑半球,9例位于第四脑室并与脑干粘连。手术全切除92例,近全切除9例。87例患者获得随访,随访时间为1~5年,术后生存率100%。所有病例均未接受放、化疗。结论小儿小脑星形细胞瘤多发生于小脑半球,小脑蚓部也不少见,影像学和组织病理有助于诊断。治疗应以显微手术全切除为主,单纯手术全切除远期预后良好。 Objective To investigate the clinical features, therapeutic strategy and prognosis of pediatric benign cerebellar astro- cytomas (BCAs). Methods 101 children with BCAs diagnosed histopathologically were analyzed retrospectively and followed up. Results There were 50 boys and 51 girls with a median age of 9.8 years old. The sizes of tumors were 3-7. 5 cm. 46 eases were with solid-tumor, 24 with the tumor in the cyst, 31 with the eysty in the tumor. 39 cases were located in cerebellum vermis, 58 eases were in the cerebellar hemisphere and 9 cases were adhesive with brain stem located in the forth ventricle. 92 cases were total removed and 9 cases were subtotal removed. 87 patients were followed up for 1-5 years, and all of them has survived, without radio- therapy or chemotherapy. Conclusion Pediatric benign cerebellar astrocytomas mostly grows in cerebellar hemisphere, also in vermis frequently. Neuroimaging and pathology may conduce to the diagnosis. Microsurgical resection may result in optimal outcome.
出处 《中国康复理论与实践》 CSCD 2009年第3期274-275,共2页 Chinese Journal of Rehabilitation Theory and Practice
关键词 小儿小脑星形细胞瘤 治疗 预后 pediatric benign cerebellar astrocytomas treatment prognosis
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参考文献10

  • 1罗世祺.小儿颅内肿瘤[M].北京:人民卫生出版社,1992:105-116.
  • 2Lach B, AI Shail E, Patay Z, et al. Spontaneous anaplasia in pilocytic astrocytoma of cerebellum[J]. Br J Neurosurg, 2003, 17(3): 250--252.
  • 3周强,邢俭,杨庆哲,任铭,相里昆.儿童后颅窝肿瘤术前脑积水分流手术的体会[J].中华神经外科杂志,2007,23(3):207-208. 被引量:15
  • 4Cushing H. Experience with the cerebellar astrocytomas. A criticial review of seventy-six cases[J]. Surg Gynecol Obstet, 1981, 53(1) : 129--204.
  • 5张玉琪 王忠诚 马振宇 等.小儿小脑星形细胞瘤影像学表现和手术治疗.中华神经外科杂志,2001,28(1):55-57.
  • 6Palma L, Russo A, Celli P. Prognosis of the so called "diffuse" cerebellar astrocytoma[J]. Neurosurgery, 1984,15: 315.
  • 7Gareia DM, Latifi HR, Simpson JR, et al. A stroeytomas of the cerebellum in children[J]. J Neurosurg, 1989, 71:661.
  • 8Steinbok P, Hentschel S, Kestle JRW. Value of postoperative surveillance imaging in the management of children with some common brain tumors[J]. J Neurosurg,1996, 84: 726.
  • 9Kleinmann GM, Schoene WO, Walshe TM, et al. Malignant transformation in benign eerebellar astrocytoma[J]. J Neurosurg, 1978, 49: 111.
  • 10Pencalet P, Maixner W, Sainte-Rose C, et al. Benign cerebellar astrocytoma in children[J]. J Neurosurg, 1999, 90: 265-- 273.

二级参考文献5

  • 1Schijman E, Peter JC, Rekate HL, et al. Management of hydrocephalus in posterior fossa tumors: how, what, when? Childs Nerv Syst, 2004, 20: 192-194.
  • 2罗世祺.儿童神经系统肿瘤.北京大学医学出版社:2006.52-70.
  • 3Santamarta D, Blazquez JA, Maillo A, et al. Analysis of cerebrospinal fluid related complications (hydrocephalus,fistula, pseudomeningocele and infection) following surgery for posterior fossa tumors. Neurocirugia (Astur), 2003, 14 : 117-126.
  • 4Bognar L, Borgulya G, Benke P, et al. Analysis of CSF shunting procedure requirement in children with posterior fossa tumors. Childs Nerv Syst, 2003, 19: 332-336.
  • 5Sainte-Rose C, Cinalli G, Roux FE, et al. Management of hydrocephalus in pediatric patients with posterior fossa tumors:the role of endoscopic third ventriculostomy. J Neurosurg,2001, 95: 791-797.

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  • 1戴慧.低分级脑星形细胞瘤术后放疗或放化疗综合治疗的临床分析[J].临床医学,2005,25(1):15-16. 被引量:1
  • 2刘玉光,朱树干,张庆林,窦以河,杨淑华.脑室腹腔分流术后并发症及其防治[J].中华外科杂志,1995,33(7):439-440. 被引量:60
  • 3段国升,朱诚,主编.手术学神经外科卷[M].北京:人民军医出版社,1994.
  • 4Davis C H, Joglekar V M. Cerebellar astrocytomas in children and young adults[ J]. J Neurol Neurosurg Psychiatry, 1981, 44 (9) : 820 - 828.
  • 5Fisher P G, Tihan T, Goldthwaite P T, et al. Outcome analysis of childhood low-grade astrocytomas [ J]. Pediatr Blood Cancer, 2008, 51(2) : 245 -250.
  • 6Villarejo F, de-Diego J M, de-la-Riva A G. Prognosis of cerebellar as- trocytomas in children[ J]. Childs Nerv Syst, 2008, 24 (2) : 203 - 210.
  • 7Lach B, A1-Shail E, Patay Z. Spontaneous anaplasia in pilocytic astro- cytoma of cerebellum[ J]. Br J Neurosurg, 2003, 17 (3) : 250 - 252.
  • 8Viano J C, Herrera E J, Suarez J C. Cerebellar astrocytomas: a 24- year experience [ J]. Childs Nerv Syst, 2001, 17 (10) : 607 -610.
  • 9Due-Tonnessen B J, Helseth E. Management of hydrocephalus in chil- dren with posterior fossa tumors : role of tumor surgery [ J ]. Pediatr Neurosurg, 2007, 43 (2) : 92 - 96.
  • 10Gudrunardottir T, Sehested A, Juhler M, et al. Cerebellar mutism: re- view of the literature [ J ]. Childs Nerv Syst, 2011, 27 (3) : 355 - 363.

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