脂肪肝与高尿酸血症的相关性研究

Study the relationship of fatty liver with hyperuricacid

目的研究脂肪肝与高尿酸血症流行病学特点、高危因素及两者的相关性。方法运用流行病学调查方法调查脂肪肝患者987例,填写相关内容,包括个人一般资料、尿酸等生化指标,应用SPSS11.0软件进行χ2检验及Logistic回归分析。结果①987例脂肪肝患者中高尿酸血症392例,男女之比为5.03∶1,男女尿酸水平比较差异具有显著性(P<0.01),男性组41～50岁达峰值(31.19%);而女性组51～60岁达峰值(21.68%);χ2检验差异具有显著性(P<0.01)。②多因素Logistic回归分析,饮酒、肥胖、高三酰甘油、高尿酸患者脂肪肝相对危险度明显增高;饮酒、超重、高三酰甘油患者高尿酸血症相对危险度明显增高。结论脂肪肝及高尿酸血症患者中青年多见,脂肪肝与高尿酸血症、肥胖、高三酰甘油密切正相关,高尿酸血症与饮酒、超重、高三酰甘油呈正相关。

[Objective] Studies of the epidemic characteristics, high-risky factors and their relationship of fatty liver and hyperuricacid. [Methods] Epidemic method were used to investigate 987 cases of fatty liver, and analyzed by SPSS 11.0 to have Χ^2 and Logistic tests. [Results] There are 392 hyperuricaeid eases among 987 fatty liver cases,and the ratio of male and female is 5.03：1. Among the male group, the patients reaching the peak are 41-50 years old （31.19%）. Among the female group, the patients reaching the peak are 51-60 years old （21.68%）. The uric acid level between male and female is obvious （P〈0.01）. Logistic tests indicate that hyperuricaeid increases related to alcohol drinker, over weight, hyper glyceride. [Conclusions] Fatty liver and hyperuricacid eases are common middle-aged and young people. Hypentrieaeid correlated positively to alcohol drinking, over weight and hyper glyceride. Fatty liver correlated positively to hyperurieacid, over weight, hyper glyceride.