克泽普用于肛肠病术后镇痛的临床观察

Clinical Observation on the Analgetic Efficacy of KeZePu after the Operation for Anorectal Disease

为观察肛肠病术后局部注射克泽普的镇痛效果，将40例行肛肠病手术患者随机分为观察组和对照组各20例。观察组术后于手术创口周围注射克泽普5～10ml；对照组术后注射生理盐水5～10ml。以视觉模拟评分法（VAS）评估疼痛程度，观察两组4，12，24，48h的疼痛情况和情绪反应等。结果显示，观察组各观察时点VAS评分均〈6分，18例各点评分〈3分，情绪稳定；对照组除4h有3例评分〈6分外，其余各点评分均〉6分，情绪不安，烦躁，强烈要求给予镇痛药物。结果表明，术后注射克泽普能较好地缓解患者的疼痛，有利于患者康复。

For the objective of observing the analgetic efficacy of local injection of KeZePu （Lidocaine hydrochloride compound） author divided 40 patients to be operated into two groups：observation group and controlled group（20 cases, each group）. After operation the patients of observation group were subjected to injection of KeZePu（5-10）ml at their peri-wound while the patients of controlled group to normal saline so- lution（5-10）ml. The evaluating pain extent with VAS method,observing the pain status and emotional re- sponse at 4,12,24 and 48h after operation were taken. As results,in the observation group at all observing time-point scores were below 6, of them 18 cases were below 3, they had stable emotion^in controlled group except for at 4h, 3 cases being below 6,other cases at all time-point were all above 6, they had emotional unstable and dysphoric manifestation, strongly demanded to be administered analgetic drug. Above-men- tioned outcome show that postoperative injection of KeZePu can better relieve pain thus help to recovery of patients.