介入治疗肺动脉栓塞疗效探讨

Effect of interventional angioplasty by thrombolysis or balloon dilation in treatment of pulmonary embolism

目的:评价介入溶栓球囊扩张术对肺动脉栓塞治疗的效果。方法:8例肺动脉栓塞患者,经股静脉穿刺插管,导管导丝置于肺动脉内进行碎栓,采用尿激酶冲击溶栓、球囊扩张术和24h持续灌注溶栓,同时给予肝素抗凝治疗。结果:完全开通3例,部分开通5例;3例氧分压均达到100%,5例氧分压在93%以上。结论:介入治疗肺动脉栓塞能及时开通肺动脉,恢复肺动脉血供,纠正低氧血症,是治疗肺动脉栓塞一种有效的方法。

Objective： To evaluate the effect of interventional angioplasty by thrombolysis or balloon dilation in treatment of pulmonary embolism. Methods： Eight patients with pulmonary embolism were treated with intervenfional angioplasty, including thrombus fragmentation, thrombolysis by persistent urokinase administration for 24-hours, or balloon dilation. Anticoagulation with heparin was maintained to prevent re-embollsm in all patients after interventional angioplasty. Results： The pulmonary artery was completely reeanallzed in three patients and partially recanalized in five patients, and saturation of blood oxygen varied from 93% to 100% after intervenfional angioplasty. Condusion： Interventional angloplasty by thrombolysis or balloon dilation can unblock the embolism and reeanalize the pulmonary artery immediately and, in turn, relieve hypoxemia, which is an effective method for pulmonary embolism.