口蹄疫疫苗研究新进展

New Research Progress of Vaccine of Food-and-mouth Disease

口蹄疫是世界性重大动物疫病之一。接种疫苗是预防该病的重要手段之一,而研制高质量、安全有效的疫苗,不但是决定疫苗免疫效果的关键,也是成功预防、控制直至最终消灭口蹄疫的先决条件。目前,除传统疫苗仍然在口蹄疫防控中扮演重要角色以外,国内外诸如亚单位疫苗、载体疫苗、核酸疫苗、基因缺失疫苗、合成肽疫苗、可饲疫苗和多表位疫苗等的研究和探索已全面展开,有望为口蹄疫的有效防控提供新的途径。

Foot-and-mouth disease is an important animal diseases. Thus highe quatative,securitive and efficient vaccine not only could determine immunol effectiveness of vaccines,but also is the prerequisite that prevent,control and eliminate foot-and-mouth disease. Traditional vaccine played an important role in preventing foot-and-mouth disease. Alternative sort of vaccines, such as subunit vaccines, vector vaccines,nucleotide vaccines, synthetic peptides vaccines, gene deletion vaccines, transgenic plant vaccines, muld-epitopes vaccines have been used all over the world.