摘要
目的调查单中心肾内科门诊慢性肾脏病（CKD）患者的基础状况，判断CKD患者肾功能下降的危险因素。方法对门诊就诊的CKD患者进行为期9个月的前瞻性横断面调查。结果共有780例CKD病例入选。前4位CKD的病因分别为原发性肾小球疾病（59．0％），高血压肾病（7．6％），狼疮肾炎（6．4％），糖尿病肾病（6．3％）。病例平均年龄41．9岁。CKD各期的分布为CKD1期47．8％、2期18．7％、3期14．0％、4期8．1％、5期11．4％。多因素回归提示年龄、蛋白尿、高血压与CKD患者的肾功能下降独立相关。结论目前针对中国CKD患者最大规模的单中心横断面调查，有助于确定CKD患者的基本状况，为进一步纵向随访奠定基础。
Objective To present the baseline characteristics of serum uric acid level in patients with chronic kidney disease（CKD） in single-centre nephrology clinic and judge the risk factor for decreased renal function of CKD patients. Methods A cross-sectional study on CKD patients in clinic was carried out for 9 months. Results 780 CKD cases were enrolled in the study. The top four causes of CKD in these patients were primary glomerular disease（59.0% ） ,essential hypertension（7.6% ）, lupus nephritis （6.4%） and diabetic nephropathy（6.3% ）. The average age was 41.9. The distribution of CKD stage was 47.8% of CKD1,18.7 % of CKD2,14.0% of CKD3,8.1% of CKD4 and 11.4% of CKDS. Multivariate Logistic regression regression analysis indicated that age, proteinuria, hypertension were independently correlated with decreased renal function. Conclusion This is the largest cross-sectional study of CKD in China, which will help to determine the basic status of Chinese CKD patients, laying a basis for further followup.
出处
《中国综合临床》
2009年第3期296-298,共3页
Clinical Medicine of China
关键词
慢性肾脏病
肾小球滤过率
横断面研究
Chronic kidney disease
Glomerular filtration rate
Cross-sectional study
