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DHA对人肝癌HepG2细胞的生长抑制作用观察 被引量:2

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摘要 体外加入二十二碳六烯酸(DHA)培养人肝癌细胞HepG2,MTT法观察细胞生长增殖情况,油红染色、荧光染色、透射电镜观察细胞形态及结构,流式细胞仪分析细胞凋亡率。结果显示,DHA能抑制HepG2生长,呈浓度和时间依赖性(P<0.01);细胞内有大量脂滴,并呈典型的凋亡改变,HepG2发生早期凋亡。认为DHA可抑制人肝癌细胞HepG2的生长,并使细胞发生早期凋亡。
出处 《山东医药》 CAS 北大核心 2009年第10期36-37,共2页 Shandong Medical Journal
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