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儿童急性肾损伤的概念与诊断 被引量：27

Conception and Diagnosis of Acute Kidney Injury in Children
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摘要 急性肾损伤(AKI)的概念将逐渐取代传统急性肾衰竭(ARF)的概念。AKI的定义为病程在3个月以内,包括血、尿、组织学及影像学检查所见的肾脏结构与功能异常。2005年的阿姆斯特丹会议同时决定将48h内血肌酐(Scr)上升≥26.5μmol/L或原Scr值增长≥50%和(或)尿量<0.5mL/(kg.h)达6h定义为AKI的诊断标准,并制定了病情分期标准。但Scr在反映肾功能的速度和精度方面存在不足,故需要寻找敏感性和特异性更好,能够预测疾病预后并具有AKI病因特异性的生物学指标。
作者 易著文
机构地区 中南大学湘雅二医院小儿肾脏病研究室
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2009年第5期321-323,共3页 Journal of Applied Clinical Pediatrics
关键词 肾损伤 急性 肾衰竭 急性 概念 诊断 生物学标志物 儿童
分类号 R726.9 [医药卫生—儿科]
  • 相关文献

参考文献15

  • 1arnoch DG. Towards a definition and classification of acute kidney injury[ J]. J Am Soc Nephrol,2005,16 ( 11 ) :3149 - 3150.
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  • 9陈香美.充分认识地震相关挤压综合征导致的急性肾损伤[J].中华肾脏病杂志,2008,24(8):527-528. 被引量：4
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二级参考文献14

  • 1Bellomo R,Ronco C,Kellum JA,et al.Acute renal failure-definition,outcome measures,animal models,fluid therapy and information technology needs:the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group[J].Crit Care,2004,8(4):204-212.
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  • 6Mehta RL,Pascual MT,Soroko S,et al.Spectrum of acute renal failure in the intensive care unit:the PICARD experience[J].Kidney Int,2004,66(4):1613-1621.
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共引文献19

同被引文献235

引证文献27

二级引证文献129

实用儿科临床杂志
2009年 第5期

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