血清总胆汁酸测定在肝胆疾病中的临床价值

Clinical Value of Serum Total Bile Acid Test in Hepatobiliary Disease

目的探讨胆汁酸(TBA)在诊断肝胆疾病中的临床价值。方法采用循环酶速率法检测了128例患者,其中33例急性肝炎患者,41例慢性肝炎患者,22例肝硬化患者,18例肝癌患者,11例胆管阻塞患者。并与56例健康对照组的血清总胆汁酸含量进行比较。结果各类肝胆疾病患者TBA均显著高于健康对照组(P<0.01),其中TBA的阳性率在急性肝炎组、肝硬化组、胆管阻塞组、肝癌组均大于85%。结论TBA检测简便实用,对肝胆疾病的临床诊断有重要的临床意义。

Objective To study the clinical value of bile acid in the diagnosis of hepatobiliary disease. Methods First,we use the circulation enzyme rate method to test 128 patients including 33patients with acute hepatitis,41 patients with chronic hepatitis ,22 patients with cirrhosis of liver, 18 patients with hepatocellular carcinoma and 11 patients with biliary obstruction. Then, we contrast the results with the serum TBA content in control group including 56 healthy people. Results The TAB content in the patients with hepatobiliary disease is significantly higher than that of the control group, in which the positive rate of TAB is higher than 85% in groups with acute hepatitis, cirrhosis of liver, bili- ary obstruction and hepatocellular carcinoma. Conclusion Detection of serum TBA is simple, practical, and has significant clinical value in the diagnosis of hepatobiliary disease.