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糖尿病表观遗传学研究进展 被引量:6

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摘要 糖尿病是21世纪严重危害人类健康的代谢性疾病。遗传、自身免疫、环境因素等均与糖尿病的发生发展密切相关。近年研究发现,糖尿病的发生和发展也受到表观遗传因素的影响。表观遗传学是基于一种可遗传的非基因序列改变而导致基因表达水平和功能的变化。传统意义上的遗传信息指的是DNA序列所提供的遗传信息,而表观遗传学信息提供了何时、何地、以何种方式去执行DNA遗传信息的指令。以下将从表观遗传修饰的角度阐述糖尿病表观遗传学国内外研究现状和发展趋势。
出处 《中华医学杂志》 CAS CSCD 北大核心 2009年第10期715-717,共3页 National Medical Journal of China
基金 基金项目:国家自然科学基金(30670991) 国家重点基础研究发展计划基金(2009CB825605,2006CB503901)
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同被引文献132

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