依达拉奉治疗急性脑梗死疗效观察

Efficacy of Edaravone in the Treatment of Acute Ischemic Stroke

目的评价依达拉奉治疗急性脑梗死的临床疗效和安全性。方法将60例急性脑梗死患者随机分为治疗组和对照组,每组30例。治疗组在对照组常规治疗基础上加用依达拉奉,比较两组的疗效。结果治疗组疗效明显优于对照组,治疗组神经功能缺损评分低于对照组,差异均有统计学意义(P<0.05)。治疗组治疗14 d后,出现转氨酶升高3例,尿素氮升高3例,均经对症治疗后降至正常。结论依达拉奉治疗急性脑梗死安全有效。

Objective To evaluate the effect of Edaravone in the treatment of acute ischemic stroke.Methods Sixty patients with acute ischemic stroke were randomly divided into two groups,the Edaravone group and control group.The patients in the trial group（edaravone group） were given Edar-avone additionally besides routine trerepy compared with those the control group.Results In the trial group as compared with in the control group,the nerve function deficiency scores were obviously lower（P〈0.05）.Conclusion Edaravone is effective in the treatment of acute ischemic stroke.