摘要
A facile and efficient 1, 4-conjungate addition(Michael addition) reaction of active methylene compounds to aft-unsaturated compounds, catalyzed by guanidinium lactate ionic liquid(IL9), has been developed. A range of chalcones and nitroalkenes together with active methylene compounds have been converted smoothly to the corresponding products in high yields.
A facile and efficient 1, 4-conjungate addition(Michael addition) reaction of active methylene compounds to aft-unsaturated compounds, catalyzed by guanidinium lactate ionic liquid(IL9), has been developed. A range of chalcones and nitroalkenes together with active methylene compounds have been converted smoothly to the corresponding products in high yields.
基金
Supported by the Jilin University Innovation Fund(No.419070200033).