尿蛋白／尿肌酐与24小时尿蛋白定量相关性分析

Clinical correlation between urine protein/urine creatinine and 24 hours total urine protein

目的探讨不同时间点尿蛋白／尿肌酐（Upro／Ucr）值与24h尿蛋白定量（24hpro）的相关性。方法选取本院住院及门诊肾脏病患者104例（312份尿标本），将晨尿与随机尿Upro／Uer与24h尿蛋白定量进行相关性分析；晨尿与随机尿Upro／Ucr进行差异分析。结果晨尿、随机尿Upro／Ucr与24h尿蛋白定量呈正相关（r晨尿=0．83，P〈0．01；r随机=0．65，P〈0．01）。晨尿与随机尿比较Upro／Ucr差异无统计学意义（P〉0．05）。结论晨尿或随机尿Upro／Ucr值可替代24h尿蛋白定量，用于监测肾脏病患者尿蛋白排泄情况。

Objective To approach the correlation between 24 hours total urine protein and ufine protein/urine creatinine at different time. Methods Selected 104 patients （312 examples of urine al- iquot）of inpatient and out- patient in our hospital, analyzed the correlation between urine protein/urine creatinine of urina sanguinis（US） and urine at random （UR）and 24 hours total urine protein and the difference between the urine protein/urine creatinine of US and that of UR. Results There was significant positive correlation between 24 hours total urine protein and urine protein/urine creatinine of US and UR （ r us =0.83, P 〈0. 001; r UB =0.65, P 〈0. 01）. There was no statistical significant between urine protein/urine creatinine of US and that of UR （ P 〉 0.05 ）. Conclusions Twenty - four hours total urine protein can be replaced by the urine protein/urine creatinine of US or UR for monitoring the excretion of urine protein of patients with kidney desease.