摘要
目的:分析抗感染药不良反应发生的情况和原因,为临床安全用药提供参考。方法:对嘉兴市药品不良反应监测中心2007年收集的809例抗感染药不良反应报告进行回顾性分析。结果:引起ADR最多的药物为头孢菌素类,发生率最高的药物是头孢曲松钠;与合并用药有关的ADR占总例数的40.30%,以静脉给药方式为主;ADR的临床表现以皮肤及其附件损害最多见,其次是消化系统和神经系统。结论:加强抗感染药临床合理应用,重视ADR监测工作,保障公众安全用药。
Objective： To analyse the adverse reaction of anti-infective drugs for their clinical safe use to supply reference. Method： Retrospectively analysis of 809 ADRs cases due to anti-infective drugs were collected by ADR Monitoring Center of Jiaxing in 2007. Result： Most of the ADR cases were induced by cephalosporins which ceftriaxone sodium was showed the highest drug;40.30% of them were induced by combined use of drugs ,which were administered chiefly through intravenous ;the most common clinical appearances were skin and its accessories damage and secondly were digestive system and nervous system reaction. Conclusion： Clinical rational use of anti-infective drugs and pay more attention to ADR monitoring must be strengthed to assure the safety of the people.
出处
《中国药师》
CAS
2009年第4期488-490,共3页
China Pharmacist
