3 649例孕妇HBV、HCV、HIV和TPPA感染血清流行病学的分析

Analysis on serological epidemiology of HBV,HCV,HIV and TPPA infection in 3 649 pregnant women

目的了解孕妇乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、艾滋病毒(HIV)和梅毒感染情况,为建立有效的防治母婴传播措施提供依据。方法对来本院做围生保健3 649例孕妇,采用ELISA法检测血清5项乙肝标志物(HBsAg、抗-HBs、HBeAg、抗-HBe和抗-HBc)、抗-HCV、抗-HIV和梅毒血清学检测(TPPA)。结果 3 649例孕妇中,HBsAg阳性率为11.13%,抗-HCV和TPPA阳性率分别为0.11%和0.36%,未检测出抗-HIV阳性孕妇。结论揭示了本市孕妇HBV、HCV、HIV和TPPA感染血清流行病学特征,建议青年男女婚前、孕前、孕期、产前应进行HBV、HCV、HIV和TPPA血清学检查,才能及早发现、及早治疗,有效阻断母婴传播,有利于优生优育。

Objective To investigate the infection status of HBV, HCV, HIV and microspironema patlidum, and to provide theoretic basis for the prevention of intrauterine infection. Methods Enzyme linked immunosorbent assay （ELISA） was applied to measuring HBV marlers （HBsAg, anti- HBs, HBeAg, anti-HBe, and anti-HBc）, anti-HCV, anti-HIV and treponema pallidum particle agglutination （TPPA） in 3 649 cases of pregnant women. Results The positive rate of HBsAg, anti- HCV and TPPA was 11. 13%, 0. 11% and 0. 36% respectively. No anti-HIV positive sample was found. Conclusion The result reveals the epidemiologic feature of HBV, HCV, HIV and microspironema pallidum infection in pregnant women in the city, and it suggests that the serologic examination of HBV, HCV, HIV and TPPA before marriage, progestation, duration of pregnancy and antepartum be essential to early diagnosis and timely treatment, blockage of intrauterine infection as well as of aristogenesis.