运用Markov模型进行药物经济学评价的概率敏感度分析

Probabilistic sensitivity analysis of pharmacoeconomics research based on Markov model

概率敏感度分析是用统计途径估计药物经济学评价中不确定性的方法,其结果用成本-效果可接受曲线总体直观给出支持干预方式具有成本-效果的依据。本文介绍常用敏感度分析方法并用实例详细阐述概率敏感度分析过程,为规范运用Markov模型进行药物经济学研究提供参考依据。

Probabilistic sensitivity analysis was a statistical approach to handing uncertainty in pharmacoeconomics evaluation, and its results could be showed as a cost-effectiveness acceptability curve, which directly summarized the evidence in favor of the intervention being cost effective. In order to give a reference for doing pharmacoeconomics research based on Markov model correctly, sensitivity analysis was recommended and probabilistic sensitivity analysis was interpreted detailedly by an example.