冠心病患者颈动脉斑块类型与发生心肌梗塞的关系

Relationship between the atherosclerotic plaque types in the carotid and the myocardial infarction with coronary artery diseases

目的探讨颈动脉斑块的不同类型与冠心病发生急性心肌梗塞的关系。方法58例临床诊断为冠心病并伴明显临床症状者,用超声检测颈动脉斑块类型、数量、厚度情况,并随访观察4-8个月,分析斑块类型与随访期内发生急性心肌梗塞的关系。结果颈动脉血管超声显示以软斑块及含有软斑块为主的混合性斑块的患者急性心肌梗塞发生率95.3%(41/43)显著高于以硬斑块为主的患者6.7%(1/15),P<0.01。斑块数量及斑块厚度与急性心肌梗塞的发生率无关。相关分析显示,只有斑块类型与急性心肌梗塞的发生相关。结论冠心病患者,超声检测颈动脉斑块性质可能具有预测急性心肌梗塞发生的作用。

Objective To evaluate the relationship between caused coronary artery diseases the types of carotid atherosclerotic plaque and myocardial infrartion. Methods The 58 patients of coronary artery disease diagnosed clinically with symptoms examined with vascular ultrasound to monitor the type, number and thickness of the atherosclerotic plaque of carotid and were followed-up for 4-8 months. The relationship between the differtent type of plaques in carotid the chance of acue myocardial infartion were analyzed. Resluts The patients with soft plaques and mixed plaques had higher rate 95.3%（41/43） of myocardial infartion＇ s attack than those with hard plaques 6.7%（1/15）,（P〈0.01）. There was correlation between plaque type and myocardial infarction , and no correlation was found between plaque number or thickness and myocardial infarction. Conclusion carotid ultrasound examnation in patients with coronary artery diseases might play an important role in predicting acute myocardial infartion.