生长抑素联合白及粉治疗急性上消化道大出血的对比研究

目的:探讨生长抑素联合白及粉对急性上消化道大出血的临床疗效。方法:将255例急性上消化道大出血患者随机分为3组,每组各85例。生长抑素联合白及粉组(A组)持续匀速静脉滴注生长抑素,并间歇予以白及糊口服或经胃管注入胃内;生长抑素组(B组)持续匀速静脉滴注生长抑素;白及粉组(C组)间歇予以白及糊口服或经胃管注入胃内。每4小时抽取胃液查隐血,并比较3组止血率和止血时间。结果:A组止血率(96.47%)优于B、C两组(86.66%);止血时间也明显快于B、C组(P<0.05)。结论:生长抑素联合白及粉对急性上消化道大出血有良好的止血疗效,无明显不良反应。

Objective： To study the clinical effects of bletilla and somatostatin in treating upper gastrointestinal bleeding. Methods ： 255 patients with upper gastrointestinal bleeding were randomly divided into three groups. 85 patients in the bletilla and soma- tostatin group（ A group） were given bletilla and somatostatin, and somatostatin group （ B group） were given somatostatin, bletilla and bletilla group （ C group） were given bleti - lla. Gastric liquid was drawn every 4 hours for occult blood test. The hemostatic rate and time were compared between the three groups. Results ： In bemostatic rate, A group was better than in B and C group（P 〈 0. 05 ）. Among patients with light bleeding, the hemostatic time in A group was shorter than in B and C group （P 〈 0.05） . Conclusion： Bletilla and somatostatin in treating upper gastrointestinal bleeding has good effect, no adverse reactions. It does not interfere with coagulation on whole body.