摘要
目的:观察多西他塞对晚期卵巢癌新辅助化疗的近期疗效及不良反应。方法:对43例晚期卵巢癌患者给予新辅助化疗的综合治疗,术前化疗采用TC或TP方案,21天为1周期,2周期后手术。结果:43例患者总有效率为74.4%(32/43),不良反应较轻患者能够耐受。有效地控制了腹水,使肿瘤松动、缩小,减少了分离癌性粘连时的出血,有利于成功进行肿瘤细胞减灭术。结论:新辅助化疗能提高晚期卵巢癌肿瘤细胞减灭术的成功率,改善预后。
Objective： To evaluate the effect and toxicity of neoadjuvant chemotherapy （NACT） with Docetaxel on treating advanced ovarian cancer. Methods：The hospi- tal records of 43 women with advanced ovarian cancer who received a compaund therapy of NACT. The chemotherapy before operation used the plan of TC or TP. The treat- ment was repeated every 21 days. The opera- tion was used after two cycles. Results： The results showed that the effective rate was 74. 4%. NACT can effectively control the aseites,making the tumor become small and decreasing the bleeding of cancer adhesion, and it will do help in the eytoreductive surgery. Conclusion： NACT can improve the succession rate of the eytoreduetive surgery in the advanced ovarian cancer,which might provide better survivals after treatment.
