摘要
目的评价系统性红斑狼疮(SLE)患者左心室功能。方法用平衡法门电路心室显像及心肌显像测定20例正常人和30例SLE患者左室收缩和舒张功能。结果SLE患者左室射血分数、相角程、高峰射血率、高峰充盈率分别为052±011、6089±1212°、308±048EDV/s和288±047EDV/s;正常对照组分别为068±002、5325±526°、366±051EDV/s和334±088EDV/s。两组比较,t值分别为450、311、580和460,P均<001。阳性率为486%,心肌显像阳性率为64%;放射性核素心脏显像检测SLE心肌损害的灵敏度为63%,特异性为85%。结论放射性核素心脏显像可以客观评价SLE患者左心室功能,对发现SLE心肌损害及指导治疗有一定意义。
Purpose To evaluate the left ventricular function of systemic lupus erythematosus (SLE) patients by equilibrium radionuclide ventriculography Methods 20 normal controls and 30 SLE patients were studied by gated cardiac blood pool imaging and gated myocardial imaging and the left ventricular systolic and diastolic parameters were analysed Results The LVEF, SH, PER and PFR of 30 SLE patients were 0 52±0 11, 60 89±12 12°, 3 08±0 48EDV/s and 2 88±0 47EDV/s While those parameters of 20 normal controls were 0 68±0 02, 53 25±5 26°, 3 66±0 51EDV/s and 3 34±0 88EDV/s, respectively The parameters of sistolic and diastolic function were significantly lower in patients than those in controls (t=4 50, 3 11, 5 80 and 4 60, P<0 01) Conclusions The cardiac function of SLE patients was lower (poorer) as compared with that of normal population Radionuclide ventriculography is useful to evaluating cardiac function in SLE patients and thereby helps with the diagnosis of the myocardial damage in the disease and guides the treatment of it
出处
《中华核医学杂志》
CAS
CSCD
北大核心
1998年第2期104-105,共2页
Chinese Journal of Nuclear Medicine