121例呼吸系统疾病患者血清淀粉样蛋白A测定结果的分析及临床意义

The analysis determination the results of 121 cases of respiratory illness in patients with serum amyloid protein A and clinical significance

目的:分析呼吸系统疾病患者血清淀粉样蛋白A(SAA)的测定结果及临床意义。方法:采用终点散射比浊法检测SAA和高敏C反应蛋白(hsCRP)水平。结果:121例患者血清SAA和hsCRP水平都比对照组有明显升高(P<0.01);且SAA治疗前后有显著性差异(P<0.01,hsCRP也有显著性差异(P<0.01),血清SAA与hsCRP水平呈正相关(治疗前:r=0.59;治疗后:r=0.67)。结论:血清SAA的检测有助于监测呼吸道患者的病程,评估患者预后和疗效。

Objective Analysis of the results of respiratory diseases in patients with serum amyloid A （SAA） determination and clinical significance . Methods The use of endpoint nephelometry assay SAA and high-sensitivity C-reactive protein （hsCRP） level. Results 121 cases of patients with SAA and hsCRP levels are significantly higher than the control group （P 〈0.01） ; and SAA before and after treatment were significantly different （P 〈0.01, hsCRP has also significantly different （P 〈0.01） , serum SAA and hsCRP level was a positive correlation （before treatment： r = 0.59; after treatment： r = 0.67） . Conclusion Detection of SAA in serum contribute to the monitoring of patients with respiratory tract disease, assess prognosis and efficacy of patients.