梅毒三种检测方法的比较

The Comparison of Three Kinds of Syphilises Examination Methods

目的比较TP-ELISA、TP-PA、TRUST三种梅毒检测方法,选择一种适合大批量标本的梅毒筛查方法。方法以TP-ELISA法检测门诊患者标本7468例,TP-ELISA阳性者以TP-PA确认,并检测TRUST。结果共检出TP-ELISA阳性116例,检出率为1.55%。其中TP-ELISA阳性、TP-PA阳性133例,符合率97.4%;TP-ELISA阳性、TP-PA阴性3例,TP-ELISA假阳性率为2.6%。113例TP-PA阳性标本中检出TRUST阳性62例,检出率54.9%(62/113);其余51例TRUST阴性,未检出率45.1%(51/113)。结论TP-ELISA是梅毒筛查的理想方法。

Objective To compare three kinds of syphilises examination methods,they are TP-ELISA,TRUST and TPPA. Choose the best one for large quantity measure of syphilises screen test. Methods Using TP-ELISA to exam 7468 patients＇ sample who are in hospital. TP-ELISA positive samples confrrrn with TP-PA,also be tested in TRUST. Results In total TP-ELISA positive sample are 116, positive rate is 1.55%. Both TP-ELISA and TPPA positive samples are 133, confirm rate is 97.6%. TP-ELISA positive but TPPA negative samples are three,TP-ELISA false positive rate is 2.6%. Among TP-PA positive samples,TRUST positive samples are 62 cases,taking up 54.9%（62/113）,the other 51 samples＇ TRUST results are negative,taking up 45.1%（51/113）. Conclusion TP-ELISA is more suitable than TRUST to be used in syphilises screen test of the hospitalization crow.