非胰岛素依赖型糖尿病危险因素的病例-对照研究

Casecontrol Study on Mulitiple Risk Factors of Non-insulindependent Diabetes Mellitus

在保定市３所医院选择１０４例Ⅱ型糖尿病人及同期条件相似的其他疾病患者进行１∶１配对并观察了２５组危险因素暴露情况，经条件Ｌｏｇｉｓｔｉｃ回归分析，有１６个因素糖尿病组高于对照组，提示为危险因素；１个因素低于对照组，表明为保护因素。多因素Ｌｏｇｉｓｔｉｃ回归模型拟合结果，动物性脂肪摄入过多（ＯＲ＝２４．０）、家族史（ＯＲ＝２２．７）等６个因素为Ⅱ型糖尿病的危险因素。

25 group risk factors of diabetes were observed in 104 pairs of case non-insulindependent diabetes mellitus(NIDDM) and normal by 1∶1 matching casecontrol sample in Baoding.22 factors were entered conditional logistic regression and 17 factors were found significance between NIDDM and normal controls(P<001).The results of mulitiple factor's logistic model fitted showed that fat over taking(OR=240),family history(OR=227) and other 4 factors were significance relative with NIDDM.