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ESRD非透析患者血清胎球蛋白A水平与左心室结构及功能的关系 被引量：1

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摘要 目的观察终末期肾病(ESRD)非透析患者血清胎球蛋白A水平,并探讨其与左心室结构及功能的关系。方法对46例ESRD非透析患者及健康对照者进行心脏超声心动图检测,采用酶联免疫吸附试验检测血清胎球蛋白A水平。结果与健康对照者比较,ESRD非透析患者血清胎球蛋白A水平明显降低(P<0.05)、左室质量指数(LVMI)显著增高(P<0.01),舒张早期最大血流速度E峰/舒张晚期最大血流速度A峰(E/A)比值显著降低(P<0.01);ESRD非透析患者左心室肥厚组较非左心室肥厚组血清胎球蛋白A水平降低(P<0.05);ESRD非透析患者血清胎球蛋白A浓度与LVMI呈负相关(P<0.05),与E/A比值呈正相关(P<0.05)。结论ESRD非透析患者体内胎球蛋白A水平显著降低,且与患者左心室结构和功能的损害程度相关。
作者 张莉莉 董斌 刘健健 李新东
机构地区 潍坊医学院 枣庄市矿务局中心医院 潍坊市人民医院
出处 《山东医药》 CAS 北大核心 2009年第13期62-63,共2页 Shandong Medical Journal
关键词 尿毒症 甲胎蛋白类 左心室
分类号 R692.5 [医药卫生—泌尿科学]
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参考文献6

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共引文献213

同被引文献24

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山东医药
2009年 第13期

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